User profiles for Zhiyuan Shen

Zhiyuan SHEN

imec
Verified email at imec.be
Cited by 740

Genomic instability and cancer: an introduction

Z Shen - Journal of molecular cell biology, 2011 - academic.oup.com
Genomic instability refers to an increased tendency of alterations in the genome during the
life cycle of cells. It is a major driving force for tumorigenesis. During a cell division, genomic …

UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins

Z Shen, PE Pardington-Purtymun, JC Comeaux… - Genomics, 1996 - Elsevier
The RAD51/RAD52-dependent DNA repair pathway is involved in DNA recombination and
DNA double-strand break repair in yeast. Although many proteins in the RAD51/RAD52-…

[HTML][HTML] Specific Interactions between the Human RAD51 and RAD52 Proteins (∗)

Z Shen, KG Cloud, DJ Chen, MS Park - Journal of Biological Chemistry, 1996 - ASBMB
Processing of DNA damage by the DNA double-strand break repair pathway in mammalian
cells is accomplished by multiprotein complexes. However, the nature of these complexes …

[HTML][HTML] LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers

…, K Lin, ZY Xu-Monette, KH Young, J Liu, Z Shen… - Nature …, 2014 - nature.com
Leukaemia inhibitory factor (LIF) has been recently identified as a p53 target gene, which
mediates the role of p53 in maternal implantation under normal physiological conditions. Here …

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

…, S Böhm, KA Bernstein, Z Shen… - Proceedings of the …, 2015 - National Acad Sciences
Damage repair mechanisms at transcriptionally active sites during the G0/G1 phase are largely
unknown. To elucidate these mechanisms, we introduced genome site-specific oxidative …

Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes

…, W Fan, GG Lennon, JS Albala, Z Shen - Nucleic acids …, 1998 - academic.oup.com
The yeast and human RAD51 genes encode strandtransfer proteins that are thought to be
involved in both recombinational repair of DNA damage and meiotic recombination. In yeast, …

Rad51 immunocytology in rat and mouse spermatocytes and oocytes

PB Moens, DJ Chen, Z Shen, N Kolas, M Tarsounas… - Chromosoma, 1997 - Springer
On the assumption that Rad51 protein plays a role in early meiotic chromosomal events, we
examine the location and time of appearance of immuno-reactive Rad51 protein in meiotic …

Reduction of circular RNA Foxo3 promotes prostate cancer progression and chemoresistance to docetaxel

Z Shen, L Zhou, C Zhang, J Xu - Cancer letters, 2020 - Elsevier
Dysregulation of circular RNA Foxo3 (circFoxo3) has been reported to be involved in breast
cancer and non-small lung cancer progression. However, little is known about the role of …

[HTML][HTML] BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage

…, R Buisson, AK Bielinsky, L Zou, Z Shen… - Nature …, 2021 - nature.com
The BRCA2 tumor suppressor protects genome integrity by promoting homologous
recombination-based repair of DNA breaks, stability of stalled DNA replication forks and DNA …

Flexible and surface-mountable piezoelectric sensor arrays for underwater sensing in marine vehicles

M Asadnia, AGP Kottapalli, Z Shen, J Miao… - IEEE Sensors …, 2013 - ieeexplore.ieee.org
In an effort to improve the situational awareness and obstacle avoidance of marine vehicles,
we fabricate, package and characterize Pb (Zr0.52Ti0.48)O3 thin-film piezoelectric pressure …