Stroke is one of the leading causes of mortality and disability worldwide. Uncovering the
cellular and molecular pathophysiological processes in stroke have been a top priority. Long …

Type 1 diabetes (T1D) is an autoimmune disease characterized by insulitis and islet β-cell
loss. Thus, an effective therapy may require β-cell restoration and immune suppression. …

ATP-sensitive potassium (K ATP) channels are weak, inward rectifiers that couple metabolic
status to cell membrane electrical activity, thus modulating many cellular functions. An …

Expression of cardiac transient outward current and inwardly rectifying K + current is age
dependent. However, little is known about age-related changes in cardiac delayed rectifier K + …

Background: Cuff-based blood pressure measurement lacks comfort and convenience. Here,
we examined whether blood pressure can be determined in a contactless manner using a …

γ-Aminobutyric acid (GABA) exerts protective and regenerative effects on mouse islet β-cells.
However, in humans it is unknown whether it can increase β-cell mass and improve …

Neuroprotective therapies which focus on factors leading to retinal ganglion cells (RGCs)
degeneration have been drawing more and more attention. The beneficial effects of nerve …

Accumulated evidence suggests that bone marrow stromal cells (BMSCs) are capable of
regenerating damaged tissue. This study evaluated whether intravenously (noninvasively) …

Autosomal recessive polycystic kidney disease is caused by mutations in PKHD1, which
encodes the membrane-associated receptor-like protein fibrocystin/polyductin (FPC). FPC …

Glioblastomas are progressive brain tumors with devastating proliferative and invasive
characteristics. Ion channels are the second largest target class for drug development. In this …