Background Since the inception of the GO annotation project, a variety of tools have been
developed that support exploring and searching the GO database. In particular, a variety of …

The most common human cancers are malignant neoplasms of the skin 1 , 2 . Incidence of
cutaneous melanoma is rising especially steeply, with minimal progress in non-surgical …

Background Many cases of hereditary breast cancer are due to mutations in either the
BRCA1 or the BRCA2 gene. The histopathological changes in these cancers are often …

With the advance of hybridization array technology researchers can measure expression
levels of sets of genes across different conditions and over time. Analysis of data produced by …

Many genes associated with CpG islands undergo de novo methylation in cancer. Studies
have suggested that the pattern of this modification may be partially determined by an …

Constantly improving gene expression profiling technologies are expected to provide
understanding and insight into cancer related cellular processes. Gene expression data is also …

This paper concerns the discovery of patterns in gene expression matrices, in which each
element gives the expression level of a given gene in a given experiment. Most existing …

An efficient algorithm is presented for detecting approximate tandem repeats in genomic
sequences. The algorithm is based on a flexible statistical model which allows a wide range of …

Computational methods for discovery of sequence elements that are enriched in a target set
compared with a background set are fundamental in molecular biology research. One …

Pulmonary fibrosis is a progressive and largely untreatable group of disorders that affects
up to 100,000 people on any given day in the United States. To elucidate the molecular …