Liquid–liquid phase separation is thought to be a key organizing principle in eukaryotic
cells to generate highly concentrated dynamic assemblies, such as the RNP granules. …

We report the study of the quenching of quantum dots (CdSe) by gold nanoparticles at the
single-molecule level. Double-stranded DNA is used as a rigid spacer to tune the distance …

Decisions on the fate of cells and their functions are dictated by the spatiotemporal dynamics
of molecular signalling networks. However, techniques to examine the dynamics of these …

The regulation of the cytoskeleton is essential for the proper organization and function of
eukaryotic cells. For instance, radial arrays of microtubules (MTs), called asters, determine the …

α-Synuclein (α-Syn) aggregation into fibrils with prion-like features is intimately associated
with Lewy pathology and various synucleinopathies. Emerging studies suggest that α-Syn …

Coordination between actin filaments and microtubules is critical to complete important steps
during cell division. For instance, cytoplasmic actin filament dynamics play an active role in …

The use of the semiconductor quantum dots (QD) as biolabels for both ensemble and single-molecule
tracking requires the development of simple and versatile methods to target …

A rhenium tris-carbonyl derivative has been designed to couple infrared and luminescent
detection in cells. Both spectroscopies are consistent with one another; they point out the …

3-Methoxy-17α-ethynylestradiol or mestranol is a prodrug for ethynylestradiol and the estrogen
component of some oral contraceptive formulations. We demonstrate here that a single …

Arsenic curative effects in APL rely on PML targeting. We report a PML B-box-2 structure that
drives trimer assembly, positioning a cysteine trio to form an arsenic-binding pocket, which …