Phase separation by ssDNA binding protein controlled via protein− protein and protein− DNA interactions

…, ZJ Kovács, R Pancsa, J Pálinkás… - Proceedings of the …, 2020 - National Acad Sciences
Bacterial single-stranded (ss)DNA-binding proteins (SSB) are essential for the replication
and maintenance of the genome. SSBs share a conserved ssDNA-binding domain, a less …

Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination

…, M Gyimesi, K Sarlós, ZJ Kovács… - Proceedings of the …, 2017 - National Acad Sciences
Cells must continuously repair inevitable DNA damage while avoiding the deleterious
consequences of imprecise repair. Distinction between legitimate and illegitimate repair …

DNA‐dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes

ZJ Kovács, GM Harami, J Pálinkás… - Protein …, 2024 - Wiley Online Library
Single‐stranded DNA binding proteins (SSBs) are ubiquitous across all domains of life and
play essential roles via stabilizing and protecting single‐stranded (ss) DNA as well as …

RecQ helicase triggers a binding mode change in the SSB–DNA complex to efficiently initiate DNA unwinding

…, M Martina, ZJ Kovács, M Kovács… - Nucleic acids …, 2017 - academic.oup.com
The single-stranded DNA binding protein (SSB) of Escherichia coli plays essential roles in
maintaining genome integrity by sequestering ssDNA and mediating DNA processing …

[HTML][HTML] The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom's syndrome helicase for efficient disruption of D-loops

GM Harami, J Pálinkás, Y Seol, ZJ Kovács… - Nature …, 2022 - nature.com
Homologous recombination (HR) is a ubiquitous and efficient process that serves the repair
of severe forms of DNA damage and the generation of genetic diversity during meiosis. HR …

Redox-dependent condensation and cytoplasmic granulation by human ssDNA binding protein 1 delineate roles in oxidative stress response

GM Harami, J Pálinkás, ZJ Kovács, B Jezsó, K Tárnok… - bioRxiv, 2023 - biorxiv.org
Human single-stranded DNA binding protein 1 (hSSB1/NABP2/OBFC2B) plays central roles
in the repair of DNA breaks and oxidized DNA lesions. Here we show that hSSB1 …

Redox-dependent phase separation and cytoplasmic granulation by human single-stranded DNA binding protein 1 (HSSB1) point to new mechanisms of cellular …

J Pálinkás, G Harami, ZJ Kovács, B Jezsó, K Tárnok… - Biophysical …, 2024 - cell.com
Single-stranded DNA binding (SSB) proteins are present in all domains of life and are
essential in protecting single-stranded (ss) DNA segments from nucleolytic cleavage and …

[PDF][PDF] Rural enterprise hub supporting rural entrepreneurship and innovation–case studies from Hungary

JK Kovács, ES Zoltán - European Countryside, 2017 - sciendo.com
Although the tendency that the population migrate from rural to urban areas is typical world
wide, the globalised economy creates new circumstances and opportunities for rural areas …

Phase separation by ssDNA binding protein controlled via protein-protein and protein-DNA interactions

GM Harami, ZJ Kovács, R Pancsa, J Pálinkás, V Baráth… - bioRxiv, 2019 - biorxiv.org
Bacterial single stranded (ss) DNA-binding proteins (SSB) are essential for the replication
and maintenance of the genome. SSBs share a conserved ssDNA-binding domain, a less …

[HTML][HTML] Device for identifying the UV emission spectrum

RJ Kovács, JZ Kovács, LA Szolga - Sensors, 2022 - mdpi.com
Nowadays, the disinfection of classrooms, shopping malls, and offices has become an
important part of our lives. One of the most effective disinfection methods is ultraviolet (UV) …