Neuronal diversity of neuropeptide signaling, including galanin, in the mouse locus coeruleus

…, S Sideromenos, Z Hevesi… - Proceedings of the …, 2023 - National Acad Sciences
The locus coeruleus (LC) is a small nucleus in the pons from which ascending and descending
projections innervate major parts of the central nervous system. Its major transmitter is …

[HTML][HTML] Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in …

Z Hevesi, J Bakker, EO Tretiakov, C Adori… - Nature …, 2024 - nature.com
The significance of transient neuropeptide expression during postnatal brain development is
unknown. Here, we show that galanin expression in the ventrobasal thalamus of infant mice …

[HTML][HTML] Adverse effects of Δ9-tetrahydrocannabinol on neuronal bioenergetics during postnatal development

J Beiersdorf, Z Hevesi, D Calvigioni, J Pyszkowski… - JCI insight, 2020 - ncbi.nlm.nih.gov
Ongoing societal changes in views on the medical and recreational roles of cannabis increased
the use of concentrated plant extracts with a Δ 9-tetrahydrocannabinol (THC) content of …

A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues

E Szodorai, Z Hevesi, L Wagner… - Proceedings of the …, 2024 - National Acad Sciences
Vesicular release of neurotransmitters and hormones relies on the dynamic assembly of the
exocytosis/trans-SNARE complex through sequential interactions of synaptobrevins, …

Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress

A Alpár, P Zahola, J Hanics, Z Hevesi… - The EMBO …, 2018 - embopress.org
Stress‐induced cortical alertness is maintained by a heightened excitability of noradrenergic
neurons innervating, notably, the prefrontal cortex. However, neither the signaling axis …

[HTML][HTML] A brainstem–hypothalamus neuronal circuit reduces feeding upon heat exposure

…, A Alpár, A Gundacker, L Afjehi, K Balueva, Z Hevesi… - Nature, 2024 - nature.com
Empirical evidence suggests that heat exposure reduces food intake. However, the neurocircuit
architecture and the signalling mechanisms that form an associative interface between …

[HTML][HTML] Chondroitin sulfate proteoglycan-5 forms perisynaptic matrix assemblies in the adult rat cortex

A Pintér, Z Hevesi, P Zahola, A Alpár, J Hanics - Cellular Signalling, 2020 - Elsevier
Composition of the brain extracellular matrix changes in time as maturation proceeds.
Chondroitin sulfate proteoglycan 5 (CSPG-5), also known as neuroglycan C, has been previously …

Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration

…, E Keimpema, G Lubec, Z Hevesi… - Proceedings of the …, 2017 - National Acad Sciences
The rostral migratory stream (RMS) is viewed as a glia-enriched conduit of forward-migrating
neuroblasts in which chemorepulsive signals control the pace of forward migration. Here …

[HTML][HTML] Tubular epithelial progenitors are excreted in urine during recovery from severe acute kidney injury and are able to expand and differentiate in vitro

D Gerges, Z Hevesi, SH Schmidt, S Kapps, S Pajenda… - PeerJ, 2022 - peerj.com
Background Acute kidney injury (AKI) is a serious condition associated with chronic kidney
disease, dialysis requirement and a high risk of death. However, there are specialized repair …

[HTML][HTML] Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer's disease

…, A Pintér, Z Máté, A Gáspárdy, Z Hevesi… - Brain Structure and …, 2019 - Springer
Calcium-binding proteins are widely used to distinguish neuronal subsets in the brain. This
study focuses on secretagogin, an EF-hand calcium sensor, to identify distinct neuronal …