[HTML][HTML] A deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/β-catenin signaling …
Background MicroRNAs (miRNAs) are a large class of tiny non-coding RNAs (~22-24 nt) that
regulate diverse biological processes at the posttranscriptional level by controlling mRNA …
regulate diverse biological processes at the posttranscriptional level by controlling mRNA …
Genetic evidence of 'genuine' empty follicle syndrome: a novel effective mutation in the LHCGR gene and review of the literature
P Yuan, Z He, L Zheng, W Wang, Y Li… - Human …, 2017 - academic.oup.com
Empty follicle syndrome (EFS) is a reproductive disorder in which no oocytes are retrieved
during IVF. The existence of genuine EFS (GEFS) is still controversial, and to date, only one …
during IVF. The existence of genuine EFS (GEFS) is still controversial, and to date, only one …
[HTML][HTML] Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness
…, Y Zhang, L Qin, Y Niu, Y Guo, X Liu, P Cong, Z He… - PloS one, 2011 - journals.plos.org
Understanding the dynamics of muscle transcriptome during development and between
breeds differing in muscle growth is necessary to uncover the complex mechanism underlying …
breeds differing in muscle growth is necessary to uncover the complex mechanism underlying …
[HTML][HTML] Understanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequencing
Porcine reproductive and respiratory syndrome (PRRS) has been one of the most economically
important diseases affecting swine industry worldwide and causes great economic …
important diseases affecting swine industry worldwide and causes great economic …
[HTML][HTML] Highly efficient generation of pigs harboring a partial deletion of the CD163 SRCR5 domain, which are fully resistant to porcine reproductive and respiratory …
C Guo, M Wang, Z Zhu, S He, H Liu, X Liu… - Frontiers in …, 2019 - frontiersin.org
Porcine reproductive and respiratory syndrome virus (PRRSV) 1 and 2 differ in their
recognition of CD163. Substitution of porcine CD163 SRCR5 domain with a human CD163-like …
recognition of CD163. Substitution of porcine CD163 SRCR5 domain with a human CD163-like …
Highly efficient targeted chromosome deletions using CRISPR/Cas9
Z He, C Proudfoot, AJ Mileham… - Biotechnology and …, 2015 - Wiley Online Library
The CRISPR/Cas9 system has emerged as an intriguing new technology for genome
engineering. It utilizes the bacterial endonuclease Cas9 which, when delivered to eukaryotic cells …
engineering. It utilizes the bacterial endonuclease Cas9 which, when delivered to eukaryotic cells …
Lipopolysaccharide‐induced miR‐1224 negatively regulates tumour necrosis factor‐α gene expression by modulating Sp1
The innate immune response provides the initial defence mechanism against infection by
other organisms. However, an excessive immune response will cause damage to host tissues. …
other organisms. However, an excessive immune response will cause damage to host tissues. …
Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs
…, R Li, J Zeng, D Mo, P Cong, X Liu, Y Chen, Z He - Transgenic …, 2019 - Springer
Insulin-like growth factor 2 (IGF2) plays an important role in the development of the foetus
and in post-natal growth and development. A SNP within intron 3 of porcine IGF2 disrupts a …
and in post-natal growth and development. A SNP within intron 3 of porcine IGF2 disrupts a …
Precise editing of myostatin signal peptide by CRISPR/Cas9 increases the muscle mass of Liang Guang Small Spotted pigs
…, X Shi, J Zeng, L Yang, D Mo, X Liu, Y Chen, Z He - Transgenic …, 2020 - Springer
Myostatin (MSTN), a member of the transforming growth factor-β superfamily, is a negative
regulator of muscle growth and development. Disruption of the MSTN gene in various …
regulator of muscle growth and development. Disruption of the MSTN gene in various …
[HTML][HTML] KDM4A regulates myogenesis by demethylating H3K9me3 of myogenic regulatory factors
Q Zhu, F Liang, S Cai, X Luo, T Duo, Z Liang, Z He… - Cell death & …, 2021 - nature.com
Histone lysine demethylase 4A (KDM4A) plays a crucial role in regulating cell proliferation,
cell differentiation, development and tumorigenesis. However, little is known about the …
cell differentiation, development and tumorigenesis. However, little is known about the …