RNAi and Heterochromatin Assembly
- 1Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724
- 2Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115-5730
- Correspondence: danesh{at}hms.harvard.edu
SUMMARY
The involvement of RNA interference (RNAi) in heterochromatin formation has become clear largely through studies in the fission yeast Schizosaccharomyces pombe and plants like Arabidopsis thaliana. This article discusses how heterochromatic small interfering RNAs are produced and how the RNAi machinery participates in the formation and function of heterochromatin.
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