CHROMOSOME ORGANIZATION AND GENIC EXPRESSION

  1. Barbara McClintock
  1. Department of Genetics, Carnegie Institution of Washington, Cold Spring Harbor, N. Y.

This extract was created in the absence of an abstract.

Excerpt

During the past six years, a study of the behavior of a number of newly arisen mutable loci in maize has been undertaken. This study has provided a unique opportunity to examine the mutation process at a number of different loci in the chromosomes. For some of these loci, several independent inceptions of instability have occurred during the progress of this study. The types of mutation that appear, and the types of instability expression, need not be the same at any one locus. In fact, comparisons of the behavior of these different mutable conditions at a particular locus have shown striking diversity, not only with regard to the changes in phenotypic expression that result from mutations at the locus, but also with regard to the manner in which mutability is controlled. Knowledge of the genetic constitutions, with respect to mutable loci already present in the plants in which new mutable...

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