X-Ray Diffraction Studies on Oriented Nucleohistone Gels

  1. J. F. Pardon,
  2. B. M. Richards, and
  3. R. I. Cotter
  1. Searle Research Laboratories, Lane End Road, High Wycombe, Buckinghamshire, England

This extract was created in the absence of an abstract.

Excerpt

X-ray diffraction techniques have been used to study nucleohistone (DNH) in a variety of experimental conditions (Luzzati and Nicolaieff, 1959, 1963; Wilkins et al., 1959; Bram and Ris, 1971). Although the results from the various studies have largely been in agreement, a series of models have been suggested to explain them. At this point in time, the available X-ray diffraction data lacks sufficient detail to enable a rigorous structure determination to be contemplated.

The various groups of workers involved in studying nucleohistone by diffraction techniques can conveniently be divided according to their lines of research: those who have studied unoriented solution and gel specimens (Luzzati and Nicolaieff, 1959, 1963; Bram and Ris, 1971), and those who, have drawn fibers from nucleohistone gels, thereby inducing molecular orientation (Wilkins et al., 1959; Pardon et al., 1967). The former group have considered both the presence of a continuous scatter profile and also the...

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