Direct Antimicrobial Resistance Prediction from MALDI-TOF mass spectra profile in clinical isolates through Machine Learning

Caroline Weis; Aline Cuénod; Bastian Rieck; Felipe Llinares-López; Olivier Dubuis; Susanne Graf; Claudia Lang; Michael Oberle; Kirstine K. Soegaard; Michael Osthoff; Karsten Borgwardt; Adrian Egli

doi:10.1101/2020.07.30.228411

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Direct Antimicrobial Resistance Prediction from MALDI-TOF mass spectra profile in clinical isolates through Machine Learning

View ORCID ProfileCaroline Weis, View ORCID ProfileAline Cuénod, View ORCID ProfileBastian Rieck, Felipe Llinares-López, Olivier Dubuis, Susanne Graf, Claudia Lang, Michael Oberle, Kirstine K. Soegaard, View ORCID ProfileMichael Osthoff, View ORCID ProfileKarsten Borgwardt, View ORCID ProfileAdrian Egli

doi: https://doi.org/10.1101/2020.07.30.228411

Caroline Weis

1Department of Biosystems and Engineering, ETH Zürich, Basel, Switzerland

2SIB Swiss Institute of Bioinformatics, Switzerland

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ORCID record for Caroline Weis
For correspondence: caroline.weis@bsse.ethz.ch karsten.borgwardt@bsse.ethz.ch adrian.egli@usb.ch

Aline Cuénod

3Applied Microbiology Research, Department of Biomedicine, University of Basel, Basel, Switzerland

4Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland

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ORCID record for Aline Cuénod

Bastian Rieck

1Department of Biosystems and Engineering, ETH Zürich, Basel, Switzerland

2SIB Swiss Institute of Bioinformatics, Switzerland

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ORCID record for Bastian Rieck

Felipe Llinares-López

1Department of Biosystems and Engineering, ETH Zürich, Basel, Switzerland

2SIB Swiss Institute of Bioinformatics, Switzerland

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Olivier Dubuis

8Clinical Microbiology, Viollier AG, Allschwil, Switzerland

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Susanne Graf

7Department for Microbiology, Cantonal Hospital Baselland, Liestal, Switzerland

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Claudia Lang

8Clinical Microbiology, Viollier AG, Allschwil, Switzerland

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Michael Oberle

9Institute for Laboratory Medicine, Medical Microbiology, Cantonal Hospital of Aarau, Aarau, Switzerland

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Kirstine K. Soegaard

3Applied Microbiology Research, Department of Biomedicine, University of Basel, Basel, Switzerland

4Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland

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Michael Osthoff

5Division of Infectious Diseases and Hospital Epidemiology, University Hospital and University of Basel, Basel, Switzerland

6Department of Internal Medicine, University Hospital and University of Basel, Basel, Switzerland

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Karsten Borgwardt

1Department of Biosystems and Engineering, ETH Zürich, Basel, Switzerland

2SIB Swiss Institute of Bioinformatics, Switzerland

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ORCID record for Karsten Borgwardt
For correspondence: caroline.weis@bsse.ethz.ch karsten.borgwardt@bsse.ethz.ch adrian.egli@usb.ch

Adrian Egli

3Applied Microbiology Research, Department of Biomedicine, University of Basel, Basel, Switzerland

4Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland

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ORCID record for Adrian Egli
For correspondence: caroline.weis@bsse.ethz.ch karsten.borgwardt@bsse.ethz.ch adrian.egli@usb.ch

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Direct Antimicrobial Resistance Prediction from MALDI-TOF mass spectra profile in clinical isolates through Machine Learning

Caroline Weis, Aline Cuénod, Bastian Rieck, Felipe Llinares-López, Olivier Dubuis, Susanne Graf, Claudia Lang, Michael Oberle, Kirstine K. Soegaard, Michael Osthoff, Karsten Borgwardt, Adrian Egli

bioRxiv 2020.07.30.228411; doi: https://doi.org/10.1101/2020.07.30.228411

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Direct Antimicrobial Resistance Prediction from MALDI-TOF mass spectra profile in clinical isolates through Machine Learning

Caroline Weis, Aline Cuénod, Bastian Rieck, Felipe Llinares-López, Olivier Dubuis, Susanne Graf, Claudia Lang, Michael Oberle, Kirstine K. Soegaard, Michael Osthoff, Karsten Borgwardt, Adrian Egli

bioRxiv 2020.07.30.228411; doi: https://doi.org/10.1101/2020.07.30.228411

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