Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies

Kushal K. Dey; Steven Gazal; Bryce van de Geijn; Samuel Sungil Kim; Joseph Nasser; Jesse M. Engreitz; Alkes L. Price

doi:10.1101/2020.09.02.279059

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Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies

View ORCID ProfileKushal K. Dey, Steven Gazal, Bryce van de Geijn, Samuel Sungil Kim, Joseph Nasser, Jesse M. Engreitz, Alkes L. Price

doi: https://doi.org/10.1101/2020.09.02.279059

Kushal K. Dey

1Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA

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ORCID record for Kushal K. Dey
For correspondence: kshldey@gmail.com

Steven Gazal

1Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA

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Bryce van de Geijn

1Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA

3Genentech, South San Francisco, CA

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Samuel Sungil Kim

1Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA

4Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA

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Joseph Nasser

5Broad Institute of MIT and Harvard, Cambridge, MA, USA

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Jesse M. Engreitz

5Broad Institute of MIT and Harvard, Cambridge, MA, USA

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Alkes L. Price

1Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA

2Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA

5Broad Institute of MIT and Harvard, Cambridge, MA, USA

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https://github.com/kkdey/GSSG
https://alkesgroup.broadinstitute.org/LDSCORE/Dey_Enhancer_MasterReg

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Posted April 01, 2021.

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Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies

Kushal K. Dey, Steven Gazal, Bryce van de Geijn, Samuel Sungil Kim, Joseph Nasser, Jesse M. Engreitz, Alkes L. Price

bioRxiv 2020.09.02.279059; doi: https://doi.org/10.1101/2020.09.02.279059

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Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies

Kushal K. Dey, Steven Gazal, Bryce van de Geijn, Samuel Sungil Kim, Joseph Nasser, Jesse M. Engreitz, Alkes L. Price

bioRxiv 2020.09.02.279059; doi: https://doi.org/10.1101/2020.09.02.279059

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