Decreased cell stiffness facilitates detachment and migration of breast cancer cells in 3D collagen matrices: An exploratory study

Ghodeejah Higgins; Jessica E Kim; Jacopo Ferruzzi; Tamer Abdalrahman; Thomas Franz; Muhammad H Zaman

doi:10.1101/2021.01.21.427639

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Decreased cell stiffness facilitates detachment and migration of breast cancer cells in 3D collagen matrices: An exploratory study

View ORCID ProfileGhodeejah Higgins, View ORCID ProfileJessica E Kim, View ORCID ProfileJacopo Ferruzzi, View ORCID ProfileTamer Abdalrahman, View ORCID ProfileThomas Franz, View ORCID ProfileMuhammad H Zaman

doi: https://doi.org/10.1101/2021.01.21.427639

Ghodeejah Higgins

1Division of Biomedical Engineering, Department of Human Biology, University of Cape Town, Observatory, South Africa

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Jessica E Kim

2Department of Biomedical Engineering, Boston University, Boston, MA, USA

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Jacopo Ferruzzi

2Department of Biomedical Engineering, Boston University, Boston, MA, USA

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Tamer Abdalrahman

1Division of Biomedical Engineering, Department of Human Biology, University of Cape Town, Observatory, South Africa

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Thomas Franz

1Division of Biomedical Engineering, Department of Human Biology, University of Cape Town, Observatory, South Africa

3Bioengineering Science Research Group, Engineering Sciences, University of Southampton, Greenfield, UK

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For correspondence: zaman@bu.edu thomas.franz@uct.ac.za

Muhammad H Zaman

2Department of Biomedical Engineering, Boston University, Boston, MA, USA

4Howard Hughes Medical Institute, Chevy Chase, MD, USA

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For correspondence: zaman@bu.edu thomas.franz@uct.ac.za

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http://doi.org/10.25375/uct.13359398

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Posted November 04, 2021.

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Decreased cell stiffness facilitates detachment and migration of breast cancer cells in 3D collagen matrices: An exploratory study

Ghodeejah Higgins, Jessica E Kim, Jacopo Ferruzzi, Tamer Abdalrahman, Thomas Franz, Muhammad H Zaman

bioRxiv 2021.01.21.427639; doi: https://doi.org/10.1101/2021.01.21.427639

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Decreased cell stiffness facilitates detachment and migration of breast cancer cells in 3D collagen matrices: An exploratory study

Ghodeejah Higgins, Jessica E Kim, Jacopo Ferruzzi, Tamer Abdalrahman, Thomas Franz, Muhammad H Zaman

bioRxiv 2021.01.21.427639; doi: https://doi.org/10.1101/2021.01.21.427639

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