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Deep Neural Networks Predict MHC-I Epitope Presentation and Transfer Learn Neoepitope Immunogenicity
View ORCID ProfileBenjamin Alexander Albert, Yunxiao Yang, Xiaoshan M. Shao, Dipika Singh, Kellie N. Smith, Valsamo Anagnostou, View ORCID ProfileRachel Karchin
doi: https://doi.org/10.1101/2022.08.29.505690
Benjamin Alexander Albert
1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
2Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
Yunxiao Yang
1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
2Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
Xiaoshan M. Shao
1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
Dipika Singh
3The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
4Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Kellie N. Smith
3The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
4Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Valsamo Anagnostou
3The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
4Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Rachel Karchin
1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
2Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA
3The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
5Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21218, USA
Posted January 18, 2023.
Deep Neural Networks Predict MHC-I Epitope Presentation and Transfer Learn Neoepitope Immunogenicity
Benjamin Alexander Albert, Yunxiao Yang, Xiaoshan M. Shao, Dipika Singh, Kellie N. Smith, Valsamo Anagnostou, Rachel Karchin
bioRxiv 2022.08.29.505690; doi: https://doi.org/10.1101/2022.08.29.505690
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