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- Anubha Mahajan1,
- Jennifer Wessel2,
- Sara M Willems3,
- Wei Zhao4,
- Neil R Robertson1,5,
- Audrey Y Chu6,7,
- Wei Gan1,
- Hidetoshi Kitajima1,
- Daniel Taliun8,
- N William Rayner1,5,9,
- Xiuqing Guo10,
- Yingchang Lu11,
- Man Li12,13,
- Richard A Jensen14,
- Yao Hu15,
- Shaofeng Huo15,
- Kurt K Lohman16,
- Weihua Zhang17,18,
- James P Cook19,
- Bram Prins9,
- Jason Flannick20,21,
- Niels Grarup22,
- Vassily Vladimirovich Trubetskoy8,
- Jasmina Kravic23,
- Young Jin Kim24,
- Denis V Rybin25,
- Hanieh Yaghootkar26,
- Martina Mñller-Nurasyid27,28,29,
- Karina Meidtner30,31,
- Ruifang Li-Gao32,33,
- Tibor V Varga34,
- Jonathan Marten35,
- Jin Li36,
- Albert Vernon Smith37,38,
- Ping An39,
- Symen Ligthart40,
- Stefan Gustafsson41,
- Giovanni Malerba42,
- Ayse Demirkan40,43,
- Juan Fernandez Tajes1,
- Valgerdur Steinthorsdottir44,
- Matthias Wuttke35,
- Cécile Lecoeur36,
- Michael Preuss10,
- Lawrence F Bielak7,
- Marielisa Graff37,
- Heather M Highland38,
- Anne E Justice37,
- Dajiang J Liu39,
- Eirini Marouli40,
- Gina Marie Peloso41,
- Helen R Warren42,
- ExomeBP Consortium43,
- MAGIC Consortium43,
- GIANT Consortium43,
- Saima Afaq15,
- Shoaib Afzal44,
- Emma Ahlqvist45,
- Peter Almgren56,
- Najaf Amin40,
- Lia B Bang57,
- Alain G Bertoni58,
- Cristina Bombieri42,
- Jette Bork-Jensen22,
- Ivan Brandslund59,60,
- Jennifer A Brody14,
- Noël P Burtt20,
- Mickaël Canouil46,
- Yii-Der Ida Chen10,
- Yoon Shin Cho61,
- Cramer Christensen62,
- Sophie V Eastwood63,
- Kai-Uwe Eckardt64,
- Krista Fischer65,
- Giovanni Gambaro66,
- Vilmantas Giedraitis67,
- Megan L Grove68,
- Hugoline G de Haan33,
- Sophie Hackinger9,
- Yang Hai10,
- Sohee Han24,
- Anne Tybjærg-Hansen54,55,69,
- Marie-France Hivert70,71,72,
- Bo Isomaa73,74,
- Susanne Jäger30,31,
- Marit E Jørgensen75,76,
- Torben Jørgensen55,77,78,
- Annemari Käräjämäki79,80,
- Bong-Jo Kim24,
- Sung Soo Kim24,
- Heikki A Koistinen81,82,83,84,
- Peter Kovacs85,
- Jennifer Kriebel31,86,
- Florian Kronenberg87,
- Kristi Läll65,88,
- Leslie A Lange89,
- Jung-Jin Lee4,
- Benjamin Lehne17,
- Huaixing Li15,
- Keng-Hung Lin90,
- Allan Linneberg77,91,92,
- Ching-Ti Liu25,
- Jun Liu40,
- Marie Loh17,93,94,
- Reedik Mägi65,
- Vasiliki Mamakou95,
- Roberta McKean-Cowdin97,
- Girish Nadkarni97,
- Matt Neville5,98,
- Sune F Nielsen53,54,55,
- Ioanna Ntalla51,
- Patricia A Peyser99,
- Wolfgang Rathmann31,100,
- Kenneth Rice101,
- Stephen S Rich102,
- Line Rode53,54,
- Olov Rolandsson103,
- Sebastian Schönherr87,
- Elizabeth Selvin12,
- Kerrin S Small104,
- Alena Stančáková105,
- Praveen Surendran106,
- Kent D Taylor10,
- Tanya M Teslovich8,
- Barbara Thorand31,107,
- Gudmar Thorleifsson44,
- Adrienne Tin108,
- Anke Tönjes109,
- Anette Varbo53,54,55,69,
- Daniel R Witte110,111,
- Andrew R Wood26,
- Pranav Yajnik8,
- Jie Yao10,
- Loïc Yengo46,
- Robin Young106,112,
- Philippe Amouyel113,
- Heiner Boeing114,
- Eric Boerwinkle68,115,
- Erwin P Bottinger11,
- Rajiv Chowdhury116,
- Francis S Collins117,
- George Dedoussis118,
- Abbas Dehghan40,119,
- Panos Deloukas51,120,
- Marco M Ferrario121,
- Jean Ferrières122,123,
- Jose C Florez70,124,125,126,
- Philippe Frossard127,
- Vilmundur Gudnason37,38,
- Tamara B Harris128,
- Susan R Heckbert129,
- Joanna M M Howson116,
- Martin Ingelsson67,
- Sekar Kathiresan20,126,130,131,
- Frank Kee132,
- Johanna Kuusisto105,
- Claudia Langenberg3,
- Lenore J Launer128,
- Cecilia M Lindgren1,20,133,
- Satu Männistö134,
- Thomas Meitinger135,136,
- Olle Melander56,
- Karen L Mohlke137,
- Marie Moitry138,139,
- Andrew D Morris140,141,
- Alison D Murray142,
- Renée de Mutsert33,
- Marju Orho-Melander143,
- Katharine R Owen5,98,
- Markus Perola134,144,
- Annette Peters29,31,107,
- Michael A Province39,
- Asif Rasheed127,
- Paul M Ridker7,126,
- Fernando Rivadineira40,145,
- Frits R Rosendaal33,
- Anders H Rosengren23,
- Veikko Salomaa134,
- Wayne H-H Sheu146,
- Rob Sladek147,148,149,
- Blair H Smith150,
- Konstantin Strauch27,151,
- André G Uitterlinden40,145,
- Rohit Varma152,
- Cristen J Willer153,154,155,
- Matthias Blüher89,109,
- Adam S Butterworth106,156,
- John Campbell Chambers17,18,157,
- Daniel I Chasman7,126,
- John Danesh106,156,158,159,
- Cornelia van Duijn40,
- Josee Dupuis6,25,
- Oscar H Franco40,
- Paul W Franks34,103,160,
- Philippe Froguel46,161,
- Harald Grallert31,86,162,163,
- Leif Groop23,144,
- Bok-Ghee Han24,
- Torben Hansen22,164,
- Andrew T Hattersley165,
- Caroline Hayward35,
- Erik Ingelsson41,166,
- Sharon LR Kardia167,
- Fredrik Karpe5,98,
- Jaspal Singh Kooner18,157,168,
- Anna Köttgen45,
- Kari Kuulasmaa134,
- Markku Laakso105,
- Xu Lin15,
- Lars Lind169,
- Yongmei Liu58,
- Ruth J F Loos11,170,
- Jonathan Marchini1,171,
- Andres Metspalu65,
- Dennis Mook-Kanamori33,172,
- Børge G Nordestgaard53,54,55,
- Colin N A Palmer173,
- James S Pankow174,
- Oluf Pedersen22,
- Bruce M Psaty175,176,
- Rainer Rauramaa177,
- Naveed Sattar178,
- Matthias B Schulze30,31,
- Nicole Soranzo9,156,179,
- Timothy D Spector104,
- Kari Stefansson38,44,
- Michael Stumvoll180,
- Unnur Thorsteinsdottir38,44,
- Tiinamaija Tuomi78,82,144,181,
- Jaakko Tuomilehto81,182,183,184,
- Nicholas J Wareham3,
- James G Wilson185,
- Eleftheria Zeggini9,
- Robert A Scott3,
- Inês Barroso9,186,
- Timothy M Frayling26,
- Mark O Goodarzi187,
- James B Meigs20,188,
- Michael Boehnke8,
- Danish Saleheen4,127,*,
- Andrew P Morris1,19,65,*,
- Jerome I Rotter189,* and
- Mark I McCarthy1,5,98,*
- 1 Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.
- 2 Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Indiana University, Indianapolis, IN, 46202-2872, USA.
- 3 MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.
- 4 Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.
- 5 Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK.
- 6 National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, 01702, USA.
- 7 Division of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, 02215, USA.
- 8 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
- 9 Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
- 10 Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, US.
- 11 The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA.
- 12 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, US.
- 13 Division of Nephrology and Hypertension, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, 84132, US.
- 14 Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA.
- 15 Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People’s Republic of China.
- 16 Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, North Carolina, 27157, USA.
- 17 Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.
- 18 Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK.
- 19 Department of Biostatistics, University of Liverpool, Liverpool, L69 3GA, UK.
- 20 Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, 02142, USA.
- 21 Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, 02114, USA.
- 22 The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2100, Denmark.
- 23 Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, 20502, Sweden.
- 24 Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea.
- 25 Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, 02118, USA.
- 26 Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX1 2LU, UK.
- 27 Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.
- 28 Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, 81377, Germany.
- 29 DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, 81675, Germany.
- 30 Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, 14558, Germany.
- 31 German Center for Diabetes Research (DZD), Neuherberg, 85764, Germany.
- 32 Department of Clinical Epidemiology, Leiden, 2300 RC, The Netherlands.
- 33 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands.
- 34 Department of Clinical Sciences, Lund University Diabetes Centre, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, SE-214 28, Sweden.
- 35 MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.
- 36 Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, 94304, US.
- 37 Icelandic Heart Assocition, Kopavogur, 201, Iceland.
- 38 Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.
- 39 Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, 63110, USA.
- 40 Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015CN, The Netherlands.
- 41 Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, 75185, Sweden.
- 42 Section of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement sciences, University of Verona, Verona, 37134, Italy.
- 43 Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands.
- 44 deCODE Genetics, Amgen inc., Reykjavik, 101, Iceland.
- 45 Institute of Genetic Epidemiology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, 79106, Germany.
- 46 CNRS-UMR8199, Lille University, Lille Pasteur Institute, Lille, 59000, France.
- 47 Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, 48109, USA.
- 48 Department of Epidemiology, University of North Carolina, Chapel Hill, NC, 27514, USA.
- 49 Human Genetics Center, The University of Texas Graduate School of Biomedical Sciences at Houston, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA.
- 50 Department of Public Health Sciences, Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA.
- 51 William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
- 52 National Institute for Health Research, Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, London, EC1M 6BQ, UK.
- 53 Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, 2730, Denmark.
- 54 The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, DK-2730, Denmark.
- 55 Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 56 Department of Clinical Sciences, Hypertension and Cardiovascular Disease, Lund University, Malmö, 20502, Sweden.
- 57 Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, 2100, Denmark.
- 58 Department of Epidemiology & Prevention, Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, 27157-1063, USA.
- 59 Institute of Regional Health Research, University of Southern Denmark, Odense, 5000, Denmark.
- 60 Department of Clinical Biochemistry, Vejle Hospital, Vejle, 7100, Denmark.
- 61 Department of Biomedical Science, Hallym University, Chuncheon, Republic of Korea.
- 62 Medical Department, Lillebælt Hospital Vejle, Vejle, Denmark.
- 63 Institute of Cardiovascular Science, University College London, London, WC1E 6BT.
- 64 Department of Nephrology and Medical Intensive Care Charité, University Medicine Berlin, Berlin, 10117, Germany.
- 65 Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.
- 66 Università Cattolica del Sacro Cuore, Roma, 00168, Italy.
- 67 Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, SE-751 85, Sweden.
- 68 Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
- 69 Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, 2100, Denmark.
- 70 Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, 02114, USA.
- 71 Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA, 02215, USA.
- 72 Department of Medicine, Universite de Sherbrooke, Sherbrooke, QC, J1K 2R1, Canada.
- 73 Malmska Municipal Health Care Center and Hospital, Jakobstad, 68601, Finland.
- 74 Folkhälsan Research Centre, Helsinki, 00014, Finland.
- 75 Steno Diabetes Center Copenhagen, Gentofte, 2820, Denmark.
- 76 National Institute of Public Health, Southern Denmark University, Copenhagen, 1353, Denmark.
- 77 Research Centre for Prevention and Health, Capital Region of Denmark, Glostrup, 2600, Denmark.
- 78 Faculty of Medicine, Aalborg University, Aalborg, Denmark.
- 79 Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.
- 80 Diabetes Center, Vaasa Health Care Center, Vaasa, Finland.
- 81 Department of Health, National Institute for Health and Welfare, Helsinki, 00271, Finland.
- 82 Endocrinology, Abdominal Center, Helsinki University Hospital, Helsinki, Finland, 00029.
- 83 Minerva Foundation Institute for Medical Research, Helsinki, Finland.
- 84 Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
- 85 Integrated Research and Treatment (IFB) Center AdiposityDiseases, University of Leipzig, Leipzig, 04103, Germany.
- 86 Research Unit of Molecular Epidemiology, Institute of Epidemiology II, Helmholtz Zentrum M¨nchen Research Center for Environmental Health, Neuherberg, 85764, Germany.
- 87 Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck, 6020, Austria.
- 88 Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia.
- 89 Department of Medicine, Division of Bioinformatics and Personalized Medicine, University of Colorado Denver, Aurora, CO, USA, 80045.
- 90 Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.
- 91 Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.
- 92 Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 93 Institute of Health Sciences, University of Oulu, Oulu, 90014, Finland.
- 94 Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore.
- 95 Dromokaiteio Psychiatric Hospital, National and Kapodistrian University of Athens, Athens, Greece.
- 96 Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, 90007, US.
- 97 Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10069, USA.
- 98 Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, OX3 7LE, UK.
- 99 Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, 48109, USA.
- 100 Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University D¨sseldorf, D¨sseldorf, Germany.
- 101 Department of Biostatistics, University of Washington, Seattle, WA, 98195-7232, USA.
- 102 Center for Public Health Genomics, Department Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia, 22908, US.
- 103 Department of Public Health and Clinical Medicine, Umeå University, Umeå, 90187, Sweden.
- 104 Department of Twin Research and Genetic Epidemiology, King’s College London, London, SE1 7EH, UK.
- 105 Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, 70210, Finland.
- 106 MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
- 107 Institute of Epidemiology II, Helmholtz Zentrum M¨nchen, German Research Center for Environmental Health, Neuherberg, 85764, Germany.
- 108 Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
- 109 Department of Medicine, University of Leipzig, Leipzig, 04103, Germany.
- 110 Department of Public Health, Aarhus University, Aarhus, Denmark.
- 111 Danish Diabetes Academy, Odense, Denmark.
- 112 Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
- 113 Institut Pasteur de Lille, INSERM U1167, Université Lille Nord de France, Lille, F-59000, France.
- 114 Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, 14558, Germany.
- 115 Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, 77030, US.
- 116 Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
- 117 Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA.
- 118 Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, 17671, Greece.
- 119 MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.
- 120 Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
- 121 Research Centre on Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Varese, 2100, Italy.
- 122 INSERM UMR 1027, Toulouse, 31000, France.
- 123 Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, 31059, France.
- 124 Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
- 125 Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, 02142, USA.
- 126 Department of Medicine, Harvard Medical School, Boston, Massachusetts, 02115, USA.
- 127 Center for Non-Communicable Diseases, Karachi, Pakistan.
- 128 Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
- 129 Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, 98195, USA.
- 130 Center for Genomic Medicine, Massachusetts General Hospital, USA.
- 131 Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
- 132 UKCRC Centre of Excellence for Public Health (NI), Queens University of Belfast, Northern Ireland, BT7 1NN, UK.
- 133 Big Data Institute, Li Ka Shing Centre For Health Information and Discovery, University of Oxford, Oxford, OX37BN, UK.
- 134 National Institute for Health and Welfare, Helsinki, 00271, Finland.
- 135 Institute of Human Genetics, Technische Universität M¨nchen, Munich, 81675, Germany.
- 136 Institute of Human Genetics, Helmholtz Zentrum M¨nchen, German Research Center for Environmental Health, Neuherberg, 85764, Germany.
- 137 Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, 27599, USA.
- 138 Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, F-67085, France.
- 139 Department of Public Health, University Hospital of Strasbourg, Strasbourg, F-67081, France.
- 140 Clinical Research Centre, Centre for Molecular Medicine, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.
- 141 The Usher Institute to the Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH16 4UX, UK.
- 142 Aberdeen Biomedical Imaging Centre, School of Medicine Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
- 143 Department of Clinical Sciences, Diabetes and Cardiovascular Disease, Genetic Epidemiology, Lund University, Malmö, 20502, Sweden.
- 144 Finnish Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.
- 145 Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015CN, The Netherlands.
- 146 Department of Internal Medicine, Taichung Veterans General Hospital, Taichung Taiwan, National Yang-Ming University, School of Medicine, Taipei, Taiwan, National Defense Medical Center, School of Medicine, Taipei, Taiwan, Taichung, 40705, Taiwan.
- 147 McGill University and Génome Québec Innovation Centre, Montreal, Quebec, H3A 0G1, Canada.
- 148 Department of Human Genetics, McGill University, Montreal, Quebec, H3A 1B1, Canada.
- 149 Division of Endocrinology and Metabolism, Department of Medicine, McGill University, Montreal, Quebec, H3A 1A1, Canada.
- 150 Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK.
- 151 Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, 80802, Germany.
- 152 USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, 90033, US.
- 153 Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, 48109, USA.
- 154 Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
- 155 Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA.
- 156 NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
- 157 Imperial College Healthcare NHS Trust, Imperial College London, London, W12 0HS, UK.
- 158 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1RQ.
- 159 British Heart Foundation, Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
- 160 Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, 02115, USA.
- 161 Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, W12 0NN, UK.
- 162 Clinical Cooparation Group Type 2 Diabetes, Helmholtz Zentrum M¨nchen, Ludwig-Maximillians University Munich, Germany.
- 163 Clinical Cooparation Group Nutrigenomics and Type 2 Diabetes, Helmholtz Zentrum M¨nchen, Technical University Munich, Germany.
- 164 Faculty of Health Sciences, University of Southern Denmark, Odense, 5000, Denmark.
- 165 University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.
- 166 Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, US.
- 167 Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, 48109, USA.
- 168 National Heart and Lung Institute, Cardiovascular Sciences, Hammersmith Campus, Imperial College London, London, W12 0NN, UK.
- 169 Department of Medical Sciences, Uppsala University, Uppsala, SE-751 85, Sweden.
- 170 Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
- 171 Department of Statistics, University of Oxford, Oxford, OX1 3TG, UK.
- 172 Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands.
- 173 Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK.
- 174 Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, 55454, US.
- 175 Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, WA, 98101-1448, USA.
- 176 Kaiser Permanent Washington Health Research Institute, Seattle, WA, 98101, USA.
- 177 Foundation for Research in Health, Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
- 178 Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8TA, UK.
- 179 Department of Hematology, School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0AH.
- 180 Divisions of Endocrinology and Nephrology, University Hospital Leipzig, Liebigstgr. 18, Leipzig, 04103, Germany.
- 181 Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland.
- 182 Dasman Diabetes Institute, Dasman, 15462, Kuwait.
- 183 Department of Neuroscience and Preventive Medicine, Danube-University Krems, Krems, 3500, Austria.
- 184 Diabetes Research Group, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
- 185 Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, 39216, USA.
- 186 Metabolic Research Laboratories, Wellcome Trust – MRC Institute of Metabolic Science, University of Cambridge, Cambridge, CB22 0QQ, UK.
- 187 Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, 90048.
- 188 General Medicine Division, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, 02114, USA.
- 189 Departments of Pediatrics and Medicine, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, US.
- Correspondence to: Anubha Mahajan (anubha{at}well.ox.ac.uk), Jerome I Rotter (jrotter{at}labiomed.org), Mark I McCarthy (mark.mccarthy{at}drl.ox.ac.uk)