Large, three-generation CEPH families reveal post-zygotic mosaicism and variability in germline mutation accumulation

Thomas A. Sasani; Brent S. Pedersen; Ziyue Gao; Lisa Baird; Molly Przeworski; Lynn B. Jorde; Aaron R. Quinlan

doi:10.1101/552117

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Large, three-generation CEPH families reveal post-zygotic mosaicism and variability in germline mutation accumulation

View ORCID ProfileThomas A. Sasani, View ORCID ProfileBrent S. Pedersen, View ORCID ProfileZiyue Gao, Lisa Baird, View ORCID ProfileMolly Przeworski, Lynn B. Jorde, View ORCID ProfileAaron R. Quinlan

doi: https://doi.org/10.1101/552117

Thomas A. Sasani

1Department of Human Genetics, University of Utah. Salt Lake City, UT

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Brent S. Pedersen

1Department of Human Genetics, University of Utah. Salt Lake City, UT

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Ziyue Gao

4Howard Hughes Medical Institute & Department of Genetics, Stanford University, Stanford, CA

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Lisa Baird

1Department of Human Genetics, University of Utah. Salt Lake City, UT

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Molly Przeworski

5Department of Biological Sciences, Columbia University, New York City, NY

6Department of Systems Biology, Columbia University, New York City, NY

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ORCID record for Molly Przeworski

Lynn B. Jorde

1Department of Human Genetics, University of Utah. Salt Lake City, UT

3USTAR Center for Genetic Discovery, University of Utah. Salt Lake City, UT

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For correspondence: lbj@genetics.utah.edu aaronquinlan@gmail.com

Aaron R. Quinlan

1Department of Human Genetics, University of Utah. Salt Lake City, UT

2Department of Biomedical Informatics, University of Utah. Salt Lake City, UT

3USTAR Center for Genetic Discovery, University of Utah. Salt Lake City, UT

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ORCID record for Aaron R. Quinlan
For correspondence: lbj@genetics.utah.edu aaronquinlan@gmail.com

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Large, three-generation CEPH families reveal post-zygotic mosaicism and variability in germline mutation accumulation

Thomas A. Sasani, Brent S. Pedersen, Ziyue Gao, Lisa Baird, Molly Przeworski, Lynn B. Jorde, Aaron R. Quinlan

bioRxiv 552117; doi: https://doi.org/10.1101/552117

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Large, three-generation CEPH families reveal post-zygotic mosaicism and variability in germline mutation accumulation

Thomas A. Sasani, Brent S. Pedersen, Ziyue Gao, Lisa Baird, Molly Przeworski, Lynn B. Jorde, Aaron R. Quinlan

bioRxiv 552117; doi: https://doi.org/10.1101/552117

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