[HTML][HTML] A novel high-throughput molecular counting method with single base-pair resolution enables accurate single-gene NIPT

DS Tsao, S Silas, BP Landry, NP Itzep, AB Nguyen… - Scientific reports, 2019 - nature.com
Next-generation DNA sequencing is currently limited by an inability to accurately count the
number of input DNA molecules. Molecular counting is particularly needed when accurate …

DNA methylation networks underlying mammalian traits

…, PW Nathanielsz, NB Nguyen, C Niehrs, B Nyamsuren… - Science, 2023 - science.org
Using DNA methylation profiles (n = 15,456) from 348 mammalian species, we constructed
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …

Optical Characterization of the SPT-3G Focal Plane

…, J Avva, RB Thakur, B Amy, B Benson… - arXiv preprint arXiv …, 2018 - arxiv.org
The third-generation South Pole Telescope camera is designed to measure the cosmic
microwave background across three frequency bands (95, 150 and 220 GHz) with ~16,000 …

Meibomian gland dropout is associated with immunodeficiency at HIV diagnosis: Implications for dry eye disease

BN Nguyen, AW Chung, E Lopez, J Silvers, HE Kent… - The Ocular Surface, 2020 - Elsevier
… (A) Bulbar conjunctival redness grade (median ± IQR); (B) Limbal conjunctival redness grade
(… (B) Negative correlation between the extent of meibomian gland dropout (%) and CD4 T-…

Buried SiGe as a performance booster in n-channel FDSOI MOSFETs

…, R Carter, J Kluth, J Schaeffer, BY Nguyen… - Solid-State …, 2019 - Elsevier
We report for the first time the implementation of SiGe buried stressors in the context of
research and development of an advanced foundry FDSOI process and the observation of …

Accelerometer determined sedentary behavior and dietary quality among US adults

K Shuval, BT Nguyen, AL Yaroch, J Drope… - Preventive …, 2015 - Elsevier
Objective Scant evidence exists pertaining to objectively measured sedentary time and dietary
quality among adults. Therefore, we examined the relationships between sedentary time, …

[HTML][HTML] Effect of body weight on early hormone levels in singleton pregnancies resulting in delivery after in vitro fertilization

RB Mejia, TW Cox, EB Nguyen, KM Summers… - Fertility and sterility, 2018 - Elsevier
Objective To evaluate which clinical characteristics influence early maternal β-human chorionic
gonadotropin (hCG) and progesterone levels in in vitro fertilization (IVF) pregnancies. …

[HTML][HTML] Antimalarial activity of 2, 6-dibenzylidenecyclohexanone derivatives

…, K Fitzsimmons, N Sienko, B Nguyen… - Bioorganic & Medicinal …, 2021 - Elsevier
Malaria remains one of the deadliest diseases on the planet, infecting an estimated 229
million individuals in 2019 with more than 400,000 associated deaths, primarily in young …

[PDF][PDF] De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

…, HI Kornblum, TW Mak, RE Looper, QD Nguyen… - Cancer cell, 2022 - cell.com
Mutations affecting isocitrate dehydrogenase (IDH) enzymes are prevalent in glioma, leukemia,
and other cancers. Although mutant IDH inhibitors are effective against leukemia, they …

Beta amyloid is neurotoxic in hippocampal slice cultures

MR Harrigan, DD Kunkel, LB Nguyen, AT Malouf - Neurobiology of aging, 1995 - Elsevier
We examined the neurotoxicity of the 40 amino acid fragment of beta amyloid peptide (Aβ1–40)
in cultured hippocampal slices. When injected into area CA3, Aβ1–40 produced …