Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms
on the transcriptome. To investigate the genetics of gene expression, we performed cis…
on the transcriptome. To investigate the genetics of gene expression, we performed cis…
Systematic identification of trans eQTLs as putative drivers of known disease associations
…, C Schurmann, J Kettunen, MW Christiansen… - Nature …, 2013 - nature.com
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …
The performance and usability of a factory-calibrated flash glucose monitoring system
T Bailey, BW Bode, MP Christiansen… - Diabetes technology & …, 2015 - liebertpub.com
Introduction: The purpose of the study was to evaluate the performance and usability of the
FreeStyle ® Libre™ Flash glucose monitoring system (Abbott Diabetes Care, Alameda, CA) …
FreeStyle ® Libre™ Flash glucose monitoring system (Abbott Diabetes Care, Alameda, CA) …
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
… However, our lead cis-eQTL SNPs show significantly different epigenetic histone mark …
We observed significant differences for 20 out of 32 tested histone marks with H3K36me3, …
We observed significant differences for 20 out of 32 tested histone marks with H3K36me3, …
[HTML][HTML] Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance
Low-fat, high-carbohydrate (LF/HC) diets commonly elevate plasma triglyceride (TG)
concentrations, but the kinetic mechanisms responsible for this effect remain uncertain. Subjects …
concentrations, but the kinetic mechanisms responsible for this effect remain uncertain. Subjects …
Safety and glycemic outcomes during the MiniMed™ advanced hybrid closed-loop system pivotal trial in adolescents and adults with type 1 diabetes
…, A Philis-Tsimikas, M Christiansen… - Diabetes technology …, 2022 - liebertpub.com
Introduction: This trial assessed safety and effectiveness of an advanced hybrid closed-loop
(AHCL) system with automated basal (Auto Basal) and automated bolus correction (Auto …
(AHCL) system with automated basal (Auto Basal) and automated bolus correction (Auto …
Increased de novo hepatic lipogenesis in human immunodeficiency virus infection
…, C Grunfeld, K Wu, M Christiansen… - The Journal of …, 1993 - academic.oup.com
We measured de novo lipogenesis in human immunodeficiency virus (HIV) infected men
using a newly developed stable isotope method. HIV-infected subjects with a history of weight …
using a newly developed stable isotope method. HIV-infected subjects with a history of weight …
The inhibition of gluconeogenesis following alcohol in humans
SQ Siler, RA Neese, MP Christiansen… - American Journal of …, 1998 - journals.physiology.org
Accurate quantification of gluconeogenic flux following alcohol ingestion in overnight-fasted
humans has yet to be reported. [2- 13 C 1 ]glycerol, [U- 13 C 6 ]glucose, [1- 2 H 1 ]galactose, …
humans has yet to be reported. [2- 13 C 1 ]glycerol, [U- 13 C 6 ]glucose, [1- 2 H 1 ]galactose, …
Clinical accuracy of a continuous glucose monitoring system with an advanced algorithm
…, A Chang, M Christiansen - Journal of diabetes …, 2014 - journals.sagepub.com
Background: We assessed the performance of a modified Dexcom G4 Platinum system with
an advanced algorithm, in comparison with frequent venous samples measured on a …
an advanced algorithm, in comparison with frequent venous samples measured on a …
Design, development, and evaluation of a novel microneedle array-based continuous glucose monitor
…, B Chua, A Chang, M Christiansen - Journal of diabetes …, 2014 - journals.sagepub.com
Background: The development of accurate, minimally invasive continuous glucose monitoring
(CGM) devices has been the subject of much work by several groups, as it is believed that …
(CGM) devices has been the subject of much work by several groups, as it is believed that …