User profiles for Christopher Krasniak

Christopher S. Krasniak

Cold Spring Harbor Laboratory
Verified email at cshl.edu
Cited by 336

[HTML][HTML] Epilepsy, behavioral abnormalities, and physiological comorbidities in syntaxin-binding protein 1 (STXBP1) mutant zebrafish

…, M Marchese, KR Hamling, MG Kumar, CS Krasniak… - PLoS one, 2016 - journals.plos.org
Mutations in the synaptic machinery gene syntaxin-binding protein 1, STXBP1 (also known
as MUNC18-1), are linked to childhood epilepsies and other neurodevelopmental disorders. …

Standardized and reproducible measurement of decision-making in mice

…, M Häusser, SB Hofer, F Hu, A Khanal, C Krasniak… - Elife, 2021 - elifesciences.org
Progress in science requires standardized assays whose results can be readily shared,
compared, and reproduced across laboratories. Reproducibility, however, has been a concern …

[HTML][HTML] Standardized and reproducible measurement of decision-making in mice

…, M Häusser, SB Hofer, F Hu, A Khanal, C Krasniak… - Elife, 2021 - ncbi.nlm.nih.gov
Progress in science requires standardized assays whose results can be readily shared,
compared, and reproduced across laboratories. Reproducibility, however, has been a concern …

Brain-wide representations of prior information in mouse decision-making

…, SB Hofer, F Hu, JM Huntenburg, A Khanal, C Krasniak… - BioRxiv, 2023 - biorxiv.org
The neural representations of prior information about the state of the world are poorly
understood. To investigate this issue, we examined brain-wide Neuropixels recordings and …

The role of CHMP2BIntron5 in autophagy and frontotemporal dementia

CS Krasniak, ST Ahmad - Brain research, 2016 - Elsevier
Charged multivesicular body protein 2B (CHMP2B) – a component of the endosomal complex
required for transport-III (ESCRT-III) – is responsible for the vital membrane deformation …

A brain-wide map of neural activity during complex behaviour

…, F Hu, F Hubert, JM Huntenburg, A Khanal, C Krasniak… - bioRxiv, 2023 - biorxiv.org
A key challenge in neuroscience is understanding how neurons in hundreds of interconnected
brain regions integrate sensory inputs with prior expectations to initiate movements. It has …

Reproducibility of in-vivo electrophysiological measurements in mice

…, M Faulkner, F Hu, J Hunterberg, A Khanal, C Krasniak… - bioRxiv, 2022 - biorxiv.org
Understanding whole-brain-scale electrophysiological recordings will rely on the collective
work of multiple labs. Because two labs recording from the same brain area often reach …

[HTML][HTML] Expression of mutant CHMP2B linked to neurodegeneration in humans disrupts circadian rhythms in Drosophila

DW Lee, X Zheng, K Shigemori, C Krasniak… - FASEB …, 2019 - ncbi.nlm.nih.gov
Mutations in CHMP2B, an ESCRT‐III (endosomal sorting complexes required for transport)
component, are associated with frontotemporal dementia (FTD) and amyotrophic lateral …

Mesoscale imaging, inactivation, and collaboration in a standardized visual decision-making task

C Krasniak - 2022 - repository.cshl.edu
Typical neuroscience experiments in the field of decision-making have focused on recording
in one or a few brain areas while animals perform a task created by and only used in their …

Correction: Standardized and reproducible measurement of decision-making in mice

…, M Häusser, SB Hofer, F Hu, A Khanal, C Krasniak… - Elife, 2022 - elifesciences.org
After publication, we realized that the text incorrectly described the quiescent period as 200-500
ms in length, whereas the mice actually experienced a quiescent period of 400-700 ms. …