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IDH1R132H acts as a tumor suppressor in glioma via epigenetic upregulation of the DNA damage response
Felipe J. Núñez, Flor M. Mendez, Padma Kadiyala, Mahmoud S. Alghamri, Masha G. Savelieff, Carl Koschmann, Anda-Alexandra Calinescu, Neha Kamran, Rohin Patel, Stephen Carney, Marissa Z. Guo, Maria B. Garcia-Fabiani, Santiago Haase, Marta Edwards, Mats Ljungman, Tingting Qin, Maureen A. Sartor, Rebecca Tagett, Sriram Venneti, Jacqueline Brosnan-Cashman, Alan Meeker, Vera Gorbunova, Lili Zhao, Daniel M. Kremer, Li Zhang, Costas A. Lyssiotis, Lindsey Jones, Cameron J. Herting, James L. Ross, Dolores Hambardzumyan, Shawn Hervey-Jumper, Maria E. Figueroa, Pedro R. Lowenstein, Maria G. Castro
doi: https://doi.org/10.1101/389817
Felipe J. Núñez
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Flor M. Mendez
2Department of Cell and Developmental Biology
Padma Kadiyala
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Mahmoud S. Alghamri
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Masha G. Savelieff
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Carl Koschmann
3Department of Pediatrics
Anda-Alexandra Calinescu
1Departments of Neurosurgery
Neha Kamran
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Rohin Patel
1Departments of Neurosurgery
Stephen Carney
1Departments of Neurosurgery
Marissa Z. Guo
1Departments of Neurosurgery
Maria B. Garcia-Fabiani
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Santiago Haase
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Marta Edwards
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Mats Ljungman
4Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
5Department of Environmental Health Science, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA
Tingting Qin
6Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA
Maureen A. Sartor
6Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA
Rebecca Tagett
6Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA
Sriram Venneti
7Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Jacqueline Brosnan-Cashman
8Departments of Pathology, Oncology and Urology, Johns Hopkins University, Baltimore, MD 21287, USA
Alan Meeker
8Departments of Pathology, Oncology and Urology, Johns Hopkins University, Baltimore, MD 21287, USA
Vera Gorbunova
9Department of Biology, University of Rochester, Rochester, NY 14627, USA
Lili Zhao
10Department of Biostatistics, University of Michigan Medical School, Ann Arbor, MI 48109
Daniel M. Kremer
11Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136-1000, USA
12Graduate Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA, 48109
Li Zhang
13Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA 48109
Costas A. Lyssiotis
11Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136-1000, USA
13Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA 48109
14Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA 48109
Lindsey Jones
16Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA
Cameron J. Herting
16Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA
17Graduate Division of Molecular and Systems Pharmacology, Emory University, Atlanta, GA, USA
James L. Ross
16Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA
18Graduate Division of Cancer Biology, Emory University, Atlanta, GA, USA
Dolores Hambardzumyan
16Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA
Shawn Hervey-Jumper
1Departments of Neurosurgery
Maria E. Figueroa
7Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
11Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136-1000, USA
Pedro R. Lowenstein
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
Maria G. Castro
1Departments of Neurosurgery
2Department of Cell and Developmental Biology
19Lead contact
Article usage
Posted August 10, 2018.
IDH1R132H acts as a tumor suppressor in glioma via epigenetic upregulation of the DNA damage response
Felipe J. Núñez, Flor M. Mendez, Padma Kadiyala, Mahmoud S. Alghamri, Masha G. Savelieff, Carl Koschmann, Anda-Alexandra Calinescu, Neha Kamran, Rohin Patel, Stephen Carney, Marissa Z. Guo, Maria B. Garcia-Fabiani, Santiago Haase, Marta Edwards, Mats Ljungman, Tingting Qin, Maureen A. Sartor, Rebecca Tagett, Sriram Venneti, Jacqueline Brosnan-Cashman, Alan Meeker, Vera Gorbunova, Lili Zhao, Daniel M. Kremer, Li Zhang, Costas A. Lyssiotis, Lindsey Jones, Cameron J. Herting, James L. Ross, Dolores Hambardzumyan, Shawn Hervey-Jumper, Maria E. Figueroa, Pedro R. Lowenstein, Maria G. Castro
bioRxiv 389817; doi: https://doi.org/10.1101/389817
IDH1R132H acts as a tumor suppressor in glioma via epigenetic upregulation of the DNA damage response
Felipe J. Núñez, Flor M. Mendez, Padma Kadiyala, Mahmoud S. Alghamri, Masha G. Savelieff, Carl Koschmann, Anda-Alexandra Calinescu, Neha Kamran, Rohin Patel, Stephen Carney, Marissa Z. Guo, Maria B. Garcia-Fabiani, Santiago Haase, Marta Edwards, Mats Ljungman, Tingting Qin, Maureen A. Sartor, Rebecca Tagett, Sriram Venneti, Jacqueline Brosnan-Cashman, Alan Meeker, Vera Gorbunova, Lili Zhao, Daniel M. Kremer, Li Zhang, Costas A. Lyssiotis, Lindsey Jones, Cameron J. Herting, James L. Ross, Dolores Hambardzumyan, Shawn Hervey-Jumper, Maria E. Figueroa, Pedro R. Lowenstein, Maria G. Castro
bioRxiv 389817; doi: https://doi.org/10.1101/389817
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