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History
- December 19, 2019.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Elsa Bernard1,2,
- Yasuhito Nannya3,
- Robert P. Hasserjian4,
- Sean M. Devlin5,
- Heinz Tuechler,
- Juan S. Medina-Martinez1,2,
- Tetsuichi Yoshizato3,
- Yusuke Shiozawa3,
- Ryunosuke Saiki3,
- Luca Malcovati6,7,
- Max F. Levine1,2,
- Juan E. Arango1,2,
- Yangyu Zhou1,2,
- Francesc Sole8,
- Catherine A. Cargo9,
- Detlef Haase10,
- Maria Creignou11,
- Ulrich Germing12,
- Yanming Zhang13,
- Gunes Gundem1,
- Araxe Sarian2,
- Arjan A. van de Loosdrecht14,
- Martin Jädersten11,
- Magnus Tobiasson11,
- Olivier Kosmider15,
- Matilde Y. Follo16,
- Felicitas Thol17,
- Ronald F. Pinheiro18,
- Valeria Santini19,
- Ioannis Kotsianidis20,
- Jacqueline Boultwood21,
- Fabio P.S. Santos22,
- Julie Schanz10,
- Senji Kasahara23,
- Takayuki Ishikawa24,
- Hisashi Tsurumi25,
- Akifumi Takaori-Kondo26,
- Toru Kiguchi27,
- Chantana Polprasert28,
- John M. Bennett29,
- Virginia M. Klimek30,
- Michael R. Savona31,
- Monika Belickova32,
- Christina Ganster10,
- Laura Palomo8,
- Guillermo Sanz33,34,
- Lionel Ades35,
- Matteo Giovanni Della Porta36,
- Alexandra G Smith37,
- Yesenia Werner1,
- Minal Patel2,
- Agnès Viale38,
- Katelynd Vanness38,
- Donna S. Neuberg39,
- Kristen E. Stevenson39,
- Kamal Menghrajani30,
- Kelly L. Bolton30,
- Pierre Fenaux35,
- Andrea Pellagatti21,
- Uwe Platzbecker40,
- Michael Heuser17,
- Peter Valent41,
- Shigeru Chiba42,
- Yasushi Miyazaki43,
- Carlo Finelli44,
- Maria Teresa Voso45,
- Lee-Yung Shih46,
- Michaela Fontenay15,
- Joop H. Jansen47,
- José Cervera48,
- Yoshiko Atsuta49,
- Norbert Gattermann12,
- Benjamin L. Ebert50,
- Rafael Bejar51,
- Peter L. Greenberg52,
- Mario Cazzola6,7,
- Eva Hellström-Lindberg11,
- Seishi Ogawa*,3 and
- Elli Papaemmanuil*,1,2,#
- 1Computational Oncology Service, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
- 2Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA
- 3Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan
- 4Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
- 5Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
- 6Department of Molecular Medicine, University of Pavia, Pavia. Italy
- 7Department of Hematology, IRCCS Fondazione Policlinico S. Matteo, Pavia. Italy
- 8MDS Group, Institut de Recerca Contra la Leucèmia Josep Carreras, Barcelona, Spain
- 9Haematological Malignancy Diagnostic Service, St James’s University Hospital, Leeds, United Kingdom
- 10Clinics of Hematology and Medical Oncology, University Medical Center. Göttingen, Germany
- 11Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
- 12Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Düsseldorf, Germany
- 13Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
- 14Department of Hematology, VU University Medical Center Amsterdam, The Netherlands
- 15Department of Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin and Université de Paris, Université Paris Descartes, Paris, France
- 16Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy
- 17Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
- 18Drug Research and Development Center, Federal University of Ceara, Ceara, Brazil
- 19MDS Unit, Hematology, AOU Careggi, University of Florence, Italy
- 20Department of Hematology, Democritus University of Thrace Medical School, Alexandroupolis, Greece
- 21Radcliffe Department of Medicine, University of Oxford and Oxford BRC Haematology Theme, Oxford, United Kingdom
- 22Oncology-Hematology Center, Hospital Israelita Albert Einstein, São Paulo, Brazil
- 23Department of Hematology, Gifu Municipal Hospital, Gifu, Japan
- 24Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan
- 25Department of Hematology, Gifu University Graduate School of Medicine, Gifu, Japan
- 26Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Japan
- 27Department of Hematology, Chugoku Central Hospital, Fukuyama, Japan
- 28Department of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand
- 29Lab. Medicine and Pathology, Hematology/Oncology, University of Rochester Medical Center, Rochester, NY, USA
- 30Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
- 31Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
- 32Department of Genomics, Institute of Hematology and Blood Transfusion, Prague, Czech Republic
- 33Department of Hematology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
- 34CIBERONC, Instituto de Salud Carlos III, Madrid, Spain
- 35Department of Hematology, hôpital St Louis, and Paris University, Paris, France
- 36Cancer Center, Humanitas Research Hospital & Humanitas University, Milan Italy
- 37Department of Health Sciences, University of York, United Kingdom
- 38Integrated Genomics Operation, Memorial Sloan Kettering Cancer Center, New York, NY, USA
- 39Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
- 40Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, University of Leipzig, Leipzig, Germany
- 41Department of Internal Medicine I, Division of Hematology and Hemostaseology and Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Austria
- 42Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
- 43Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Japan
- 44Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
- 45MDS Cooperative Group GROM-L, Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy
- 46Chang Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan
- 47Laboratory Hematology, Deptartment LABGK, Radboud University Medical Centre, Nijmegen, The Netherlands
- 48Department of Hematology and Genetics Unit, University Hospital La Fe, Valencia, Spain
- 49Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan
- 50Department of Medical Oncology and Howard Hughes Medical Institute, Dana-Farber Cancer Center, Boston, MA, USA
- 51UC San Diego Moores Cancer Center, La Jolla, California, USA
- 52Stanford University Cancer Institute, Stanford, CA, USA
- ↵#Address for correspondence: papaemme{at}mskcc.org