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Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development
Ana Lima, Gabriele Lubatti, Jörg Burgstaller, Di Hu, Alistair Green, Aida Di Gregorio, Tamzin Zawadzki, Barbara Pernaute, Elmir Mahammadov, Salvador Perez Montero, Marian Dore, Juan Miguel Sanchez, Sarah Bowling, Margarida Sancho, Mohammad Karimi, David Carling, Nick Jones, Shankar Srinivas, Antonio Scialdone, View ORCID ProfileTristan A. Rodriguez
doi: https://doi.org/10.1101/2020.01.15.900613
Ana Lima
1National Heart and Lung Institute, Imperial College London, UK
2MRC London Institute of Medical Sciences (LMS), Institute of Clinical Sciences, Imperial College London, UK
Gabriele Lubatti
3Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Munich, Germany
4Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany
5Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany
Jörg Burgstaller
6Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria
Di Hu
7Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
Alistair Green
8Department of Mathematics, Imperial College London, UK.
Aida Di Gregorio
1National Heart and Lung Institute, Imperial College London, UK
Tamzin Zawadzki
1National Heart and Lung Institute, Imperial College London, UK
Barbara Pernaute
1National Heart and Lung Institute, Imperial College London, UK
9Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain
Elmir Mahammadov
3Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Munich, Germany
4Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany
5Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany
Salvador Perez Montero
1National Heart and Lung Institute, Imperial College London, UK
Marian Dore
2MRC London Institute of Medical Sciences (LMS), Institute of Clinical Sciences, Imperial College London, UK
Juan Miguel Sanchez
1National Heart and Lung Institute, Imperial College London, UK
Sarah Bowling
1National Heart and Lung Institute, Imperial College London, UK
Margarida Sancho
1National Heart and Lung Institute, Imperial College London, UK
Mohammad Karimi
2MRC London Institute of Medical Sciences (LMS), Institute of Clinical Sciences, Imperial College London, UK
10Comprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King’s College London, Denmark Hill, London SE5 9NU, UK.
David Carling
2MRC London Institute of Medical Sciences (LMS), Institute of Clinical Sciences, Imperial College London, UK
Nick Jones
8Department of Mathematics, Imperial College London, UK.
Shankar Srinivas
7Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
Antonio Scialdone
3Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Munich, Germany
4Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany
5Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany
Tristan A. Rodriguez
1National Heart and Lung Institute, Imperial College London, UK
Article usage
Posted January 15, 2021.
Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development
Ana Lima, Gabriele Lubatti, Jörg Burgstaller, Di Hu, Alistair Green, Aida Di Gregorio, Tamzin Zawadzki, Barbara Pernaute, Elmir Mahammadov, Salvador Perez Montero, Marian Dore, Juan Miguel Sanchez, Sarah Bowling, Margarida Sancho, Mohammad Karimi, David Carling, Nick Jones, Shankar Srinivas, Antonio Scialdone, Tristan A. Rodriguez
bioRxiv 2020.01.15.900613; doi: https://doi.org/10.1101/2020.01.15.900613
Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development
Ana Lima, Gabriele Lubatti, Jörg Burgstaller, Di Hu, Alistair Green, Aida Di Gregorio, Tamzin Zawadzki, Barbara Pernaute, Elmir Mahammadov, Salvador Perez Montero, Marian Dore, Juan Miguel Sanchez, Sarah Bowling, Margarida Sancho, Mohammad Karimi, David Carling, Nick Jones, Shankar Srinivas, Antonio Scialdone, Tristan A. Rodriguez
bioRxiv 2020.01.15.900613; doi: https://doi.org/10.1101/2020.01.15.900613
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