Abstract
Episodic recall depends upon the reinstatement of cortical activity present during the formation of a memory. We identified dissociable cortical networks via functional connectivity that uniquely reinstated semantic content and temporal context of previously studied stimuli during free recall. Network-specific reinstatement predicted the temporal and semantic organization of recall sequences, demonstrating how specialized cortical systems enable the human brain to target specific memories.
Competing Interest Statement
M.R.S. is the principal investigator (PI) of research contracts with SK Life Science, Takeda, UCB Pharma, Neurelis, Eisai, Medtronic, Engage, and Cavion. M.R.S. serves as a consultant to Medtronic through Jefferson University which receives all compensation for these services. B.C.J. has research contracts with Neuropace, Medtronic, Sunovion, and Eisai. R.E.G. servers as a consultant to Medtronic, a subcontractor on the RAMproject. R.E.G. receives compensation for these services; the terms of this arrangement have been reviewed and approved by Emory University in accordance with its conflict of interest policies. The remaining authors declare no competing interests.