A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition

Yuichi Shichino; Mari Mito; Kazuhiro Kashiwagi; Mari Takahashi; Takuhiro Ito; Nicholas T. Ingolia; Shintaro Iwasaki

doi:10.1101/2021.09.18.460932

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A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition

View ORCID ProfileYuichi Shichino, View ORCID ProfileMari Mito, View ORCID ProfileKazuhiro Kashiwagi, View ORCID ProfileMari Takahashi, View ORCID ProfileTakuhiro Ito, View ORCID ProfileNicholas T. Ingolia, View ORCID ProfileShintaro Iwasaki

doi: https://doi.org/10.1101/2021.09.18.460932

Yuichi Shichino

1RNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama 351-0198, Japan

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Mari Mito

1RNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama 351-0198, Japan

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Kazuhiro Kashiwagi

2Laboratory for Translation Structural Biology, RIKEN Center for Biosystems Dynamics Research, Tsurumi-ku, Yokohama 230-0045, Japan

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Mari Takahashi

2Laboratory for Translation Structural Biology, RIKEN Center for Biosystems Dynamics Research, Tsurumi-ku, Yokohama 230-0045, Japan

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Takuhiro Ito

2Laboratory for Translation Structural Biology, RIKEN Center for Biosystems Dynamics Research, Tsurumi-ku, Yokohama 230-0045, Japan

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Nicholas T. Ingolia

3Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 USA

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Shintaro Iwasaki

1RNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama 351-0198, Japan

4Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba 277-8561, Japan

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For correspondence: shintaro.iwasaki@riken.jp

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Posted September 19, 2021.

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A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition

Yuichi Shichino, Mari Mito, Kazuhiro Kashiwagi, Mari Takahashi, Takuhiro Ito, Nicholas T. Ingolia, Shintaro Iwasaki

bioRxiv 2021.09.18.460932; doi: https://doi.org/10.1101/2021.09.18.460932

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A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition

Yuichi Shichino, Mari Mito, Kazuhiro Kashiwagi, Mari Takahashi, Takuhiro Ito, Nicholas T. Ingolia, Shintaro Iwasaki

bioRxiv 2021.09.18.460932; doi: https://doi.org/10.1101/2021.09.18.460932

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